Biological activity of lignicolous marine micromycetes isolated from palmar's mangrove - provincia de santa Elena

Abstract

Marine fungi are a group of microorganisms capable of biosynthesized metabolites with novel structures. Generally microbial population produces compounds that work against the growth of other populations. Antibiotics produced naturally by these populations, could provide benefits in the control of diseases, both in aquaculture and in human and animal pathology, in this context tropical fungi are entering in screening programs as potential producers of drugs with new models of action. In the present investigation two protocols were established to evaluate the bioactivity ofmarine fungi against Gram positive and Gram negative bacteria: fungal extracts and fungal discs. There was no bioactivity in bioassays offungal extracts ofmarine ascomycete versus Gram negative bacteria Rhodospirillum sp. and Pseudomonas sp. Methods of preservation to fungal extracts at 4 and -20ºC were suitable for conservation, there was no loss of volume or change in color of the extracts or any other signs of deterioration, there was no fungal or bacterial contamination. None of fungal discs bioassays of marine ascomycetes versus Gram negative bacteria Enterobacter sp, Escherichia coli, E. coli001, Klebsiella sp., Klebsiella sp.001, and the Gram positive bacterium Staphylococcus sp. were observed inhibition of bacterial growth.