Alternativa en el tratamiento de la mastopatia fibroquística con tamoxifeno
DOI:
https://doi.org/10.53591/rug.v91i3.1017Abstract
This study include 50 patients, between May/93 to April/94.
aged 18 - 53 years, randomly recruited from clinic of breast.
of gynecological senlice of the IESS "TEODORO MALDONADO CARBO" Hospital of Guayaquil city, with diagnosis of fibrocystic rnastophaty. The patiens clinical history was recorder, physical examination, hormona perfile (proiactine), Ultrasound of breast
and rnammographic in patients older iban 35 years or those requiring so. Treatment was started with 10mg day of TAMOXIFEN for 4 months.
At the end of therapy, hormone perfile. Ultrasound of the breast and physical examination were repeled for control pourposes. We obtained the following results; mean age was 35 years old, Fibrocystic Mastophaty was most frequent in women aged 31-40 years, mean age for menarche was 12 years in 56% of patients, no antecedent of pregnancy in 36%
of patients, breast feeding antecedent in 64% of cases. The breast painful disappeared in 94%,
The prolactine level were normal in 48 patients, 2 patients high level of prolactine were exclude physical examination and ultrasound showed improvement till 4 month and 12 month post therapy. We did no have side effects secondays in 35 patients and light siete effects in 13 patients, but were able to continue therapy.
Because of this, our recommendation as a good alternative in the treatment of fibrocystic mastophaty is the TAMOXIFEN for 4 months.
Metrics
References
-B. Cupceaneu Endocrinología Journal.- Julio-Sept. 1985. Tratamiento a Corto plazo con Tarnoxifeno. En Displasias Mamarias de origen benigno.
.- B. Cupceaneu Endocrinología Journal.- Octr-Dic. 1985. Tratamiento combinado de Tamoxifeno Linestrenol en las Displasias mamarias de origen benigno
- Carolyn D, Runowicz Md., Gary L. Golberg Med. Harriet O_ Smith Med_ Detección de Cáncer de mama en mujeres mayores de 40 años. en Clínicas de Norteaméríca de Ginecología y Obstetricia Vil 1993.
- David F.C. Gibson Md. Y.V. Craig Jordan. Antiestrógeno como tratamiento coadyuvante para el cancer de mama. Pasado, presente y futuro, en Clinica de Norteamérica Vol, V.1990. Cáncer mamario estrategia para el decenio.
- Dogliotti L. Mansel R, E. Fibrocyslic Breast Disease Symposium at the With World Congress of Gynecology asid Obsielries. Berlin, Sept. 1985.
- Febres F. B. Fisiologia Hormonal de la Mastopatía Fibroquística en avances en Mastologia Ed. Universitaria Santiago de Chile, 1992.
- Godman y .Gilman. Las bases farmacológicas de la Terapéutica Médica. Editorial Médica Panamericana, 1991
- Hernández Muñoz G. Avances en Mastología. Editorial Universitaria S.A. Santiago de Chile, 1992.
- J A. Furr y V.C. Jordan Farmacology Terapy (England) Usos Clínicos y Farmacológicos del Tarnoxifeno. 1984
- Joane T. Piscitelli y Roo T, Parket Cuidados Primarios en la mujer rnenopáusica en Clínica Obstétrica y Ginecológica. Volumen 2. 1986.
- Pérez Manga G. Cáncer, de mama. Editorial MCR S.A. Mallorca Barcelona 1989.
- Puga Pieri, Tratamiento de Diplasia Severa con Tamoxfeno. Clinica Alemana Santiago de Chile 1987,
- SiTruck Ware, R. Stervers. Mauvais Jarvis P. Benign Breast Disease Hormonal investigation Obst. Ginecol 53-1979.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 1994 Manuel Baquerizo Olaya, Nelson Bueno Suárez, Nelly Parra Paredes, Mirella Franco Tumbaco
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Authors who publish in Revista de la Universidad de Guayaquil know and accept the following conditions:
- The authors retain the copyright in the works, and grant to Revista de la Universidad de Guayaquil the right of the first publication of the work, under an international license Creative Commons Attribution-NonComderderivatives 4.0 that allows third parties to share the work provided that its author and its first publication is indicated this journal.
- The authors retain copyright and guarantee to Revista de la Universidad de Guayaquil the right to publish the work through the channels it deems appropriate.
- The authors are free to share, copy, distribute, execute and publicly communicate the version of the work published in Revista de la Universidad de Guayaquil, recognizing its publication in this journal.
- The authors are authorized to disseminate their works electronically once they are accepted for publication.