Efectos de la disbiosis en la cavidad oral y su relación con la enfermedad de Parkinson Effects of dysbiosis in the oral cavity and its relationship with Parkinson's disease

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Edelyn Jael Cabrales Tapia
Santiago Andrés López Jurado

Resumen

Introducción: El desequilibrio en los mediadores inflamatorios ha formado la base del vínculo propuesto entre disbiosis oral y el desarrollo y la progresión de la enfermedad de Parkinson, siendo el vínculo entre los dos la "inflamación. Objetivos: Determinar los efectos de la disbiosis en cavidad oral y su relación con la Enfermedad de Parkinson. Materiales y métodos: investigación de tipo bibliográfico documental, de enfoque cualitativo, retrospectivo en la búsqueda, de diseño descriptivo y analítico, de método deductivo.   Mediante uso de análisis PICO, palabras clave y términos mesh “Parkinson’s disease and Oral Dysbiosis”, “Inflammation and Parkinson’s, se utilizaron los buscadores: Pubemed, Scielo, ELsevier. Se revisaron 1150 documentos, que por criterios de inclusión y exclusión quedaron en 68. Análisis y discusión de resultados: Varios autores sugieren que los patógenos orales están involucrados en un proceso de neuroinflamación y caída de la barrera hematocefálica, lo que provocara el inicio o progresión de la enfermedad de Parkinson según algunos estudios. Conclusión: Si bien la evidencia debería ser mayor, muchos estudios indican que los patógenos orales pueden iniciar o ser un coadyuvante para el progreso de la enfermedad de Parkinson. A su vez esta enfermedad a causa degeneración motora por lo que se ve afecta la higiene oral, además estos pacientes usan ciertos fármacos que ocasionan xerostomía, por lo cual se ven afectados con mayor frecuencia por enfermedades periodontales. 


 

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Cabrales Tapia EJ, López Jurado SA. Efectos de la disbiosis en la cavidad oral y su relación con la enfermedad de Parkinson: Effects of dysbiosis in the oral cavity and its relationship with Parkinson’s disease. EOUG [Internet]. 12 de enero de 2022 [citado 29 de junio de 2022];5(1):38-46. Disponible en: https://revistas.ug.edu.ec/index.php/eoug/article/view/1400
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Biografía del autor/a

Edelyn Jael Cabrales Tapia, Universidad Católica de Santiago de Guayaquil

Odontóloga. Universidad Católica de Santiago de Guayaquil, Ecuador

https://orcid.org/0000-0003-1521-7651

Santiago Andrés López Jurado, Universidad Católica de Santiago de Guayaquil

Especialista en Periodoncia. Docente Universidad Católica de Santiago de Guayaquil, Ecuador

https://orcid.org/0000-0002-1279-9011

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